However, it remains unclear how, and to what extent, miRNAs coordinate animal survival and development in response to stresses. However, the mechanisms that coordinate the long-term survival, overall developmental arrest, and reinitiation remain to be investigated. However, when newly hatched L1 worms encounter an environment with no food, developmental programs arrest and the worm enters L1 diapause. When late, first larval stage (L1) worms sense unfavorable conditions, they enter an alternative and long-lived larval stage called dauer larvae (or dauer diapause). The nematode Caenorhabditis elegans responds to starvation by entering developmental arrest at multiple stages of its life cycle (1). Extreme climate events such as droughts and heatwaves are intensifying under climate change, yet their combined effects on plant recovery remain unclear.
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